Mitochondrial glutathione redox cycle and interaction with other antioxidant MedLink Neurology Journal of Cellular Biochemistry Wiley Online Library Frontiers Glutathione levels are associated with methotrexate resistance in acute lymphoblastic leukemia cell lines Leucovorin (Folinic Acid) The Rescue Drug! Pearl:Leucovorin (Folinic Acid) is Methotrexate's antidote. It is the reduced form of folate that can bypass the enzyme dihydrofolate reductase (which Methotrexate inhibits). Application: It Molecular toxicity of methotrexate in rheumatoid arthritis treatment: A novel perspective and therapeutic implications ScienceDirect Thermally responsive and reduced glutathione sensitive folate targeted nanocarrier based on alginate and pluronic F127 for on demand release of methotrexate ScienceDirect
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